BDBM103727 US10112907, Example 00033::US10206907, Compound 200::US10708263, Compound 1::US10766894, Compound TABLE 1.18::US10919890, Compound 1::US10961228, Example Filgotinib::US11000528, Cpd # 1::US11203595, TABLE 1.18::US11279699, Compound Filgotinib::US8563545, 1
SMILES O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
InChI Key InChIKey=RIJLVEAXPNLDTC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 103727
Affinity DataIC50: 72.7nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 73.8nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 79.1nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 86.8nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibition of Tyk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Recombinant human TYK2 catalytic domain (amino acids 871-1187; catalog number 08-147) is purchased from Carna biosciences. 5 ng of TYK2 is incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr followed by anti-pSTAT1 antibody addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human Tyk2 expressed in sf21 baculovirus expression system assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of recombinant human TYK2 using GGMEDIYFEFMGGKKK as substrate incubated for 40 mins in presence of Mg/ATP mixture by [gamma p33]-ATP based...More data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair